Product Introduction
17α-Hydroxyprogesterone (17-OHP) is an endogenous steroid intermediate involved in adrenal and gonadal steroid biosynthesis. It is a key precursor in the metabolic pathway leading to cortisol, progesterone, testosterone, and estrogen production.
In clinical diagnostics, it is widely used as a biomarker for congenital adrenal hyperplasia (CAH), especially 21-hydroxylase deficiency screening.
What is 17α-Hydroxyprogesterone Powder?
Product Information
|
Item |
Specification |
|
Product Name |
17α-Hydroxyprogesterone |
|
CAS Number |
68-96-2 |
|
EINECS |
200-699-4 |
|
Molecular Formula |
C21H30O3 |
|
Molecular Weight |
330.46 g/mol |
|
Appearance |
White to off-white powder |
|
Specification |
99% |
|
Shelf Life |
2 years |
|
Storage |
2–8°C, airtight, light-protected |
Mechanism Summary
17α-Hydroxyprogesterone is a steroidal intermediate with multiple biological roles:
- Intermediate in cortisol and sex hormone biosynthesis
- Progesterone receptor (PR) agonist activity
- Weak glucocorticoid receptor (GR) partial activity
- Mineralocorticoid receptor (MR) antagonistic behavior
- Produced mainly in adrenal cortex and gonads
Applications
Endocrinology Research
Steroid biosynthesis pathway studies
Adrenal gland function research
Hormonal regulation mechanism analysis
Diagnostic Development
CAH (Congenital Adrenal Hyperplasia) screening assays
21-hydroxylase deficiency biomarker calibration
Immunoassay (ELISA / LC-MS standard) development
Pharmaceutical Research
Steroid receptor interaction studies
Hormone metabolism pathway modeling
Enzyme kinetics and inhibition research
Quality Control System
Each batch is manufactured under GMP-controlled conditions and released only after full QC review.
|
Test Item |
Method |
Specification |
|
Assay |
HPLC |
≥ 99.0% |
|
Identification |
IR / HPLC |
Conforms |
|
Water Content |
Karl Fischer |
≤ 0.5% |
|
Residual Solvents |
GC (ICH Q3C) |
Compliant |
|
Related Substances |
HPLC |
Controlled impurity profile |
|
Heavy Metals |
ICP-MS |
≤ 10 ppm |
Manufacturing System
Produced in a GMP-certified facility equipped with:
HPLC / GC / NMR analytical systems
Controlled clean production environment
SOP-based manufacturing workflow
Batch-level traceability system
Compliance:
GMP (Good Manufacturing Practice)
ISO 9001:2015
ICH guideline-based QC standards
Packaging & Shipping
We provide export-grade pharmaceutical packaging designed for stability and international transport safety:
Primary packaging: Vacuum-sealed aluminum foil bag
Secondary packaging: Double PE liner
Tertiary packaging: Fiber drum / export carton
Standard sizes: 10g / 100g / 1kg / 5kg / 25kg
Label includes: CAS, batch no., production date, storage condition
Shipping options:
Air freight / Sea freight / Express courier
Temperature-controlled shipping available
International chemical transport compliant
Customization Services
We support flexible OEM/ODM and research customization:
Purity levels: 98% / 99% / customized
Impurity control profiles tailored to client needs
Small research packaging (10mg–1g)
Bulk industrial supply (1kg–25kg)
Private label packaging available
Technical documentation customization (COA / TDS / MSDS format)
Certifications & Documentation
Available upon request:
GMP Certificate
ISO 9001:2015 Certificate
COA (Certificate of Analysis)
MSDS (Material Safety Data Sheet)
Technical Data Sheet (TDS)
Stability data report (selected batches)
Frequently Asked Questions
Q: What payment methods do you accept?
A: We accept T/T (bank transfer), L/C at sight for bulk orders, and sample orders via PayPal or Western Union.
Q: What are your trade terms (Incoterms)?
A: We support EXW, FOB, CIF, and DDP depending on destination and order volume.
Q: What is your MOQ (Minimum Order Quantity)?
A: MOQ for research samples starts from 10g, while bulk industrial orders typically start from 1kg.
Q: What is your lead time / delivery time?
A: Sample orders are shipped within 3–5 days, and bulk orders are typically delivered within 7–15 working days depending on quantity.
Q: How do you ensure product quality consistency?
A: Each batch undergoes strict HPLC/GC/ICP-MS testing under GMP-controlled SOPs, and only qualified batches with full COA approval are released.
Q: What certifications do your products and facility have?
A: Our facility is GMP-compliant and ISO 9001:2015 certified, and we provide COA, MSDS, and regulatory documentation for each batch.
Q: What packaging options are available?
A: We offer vacuum-sealed aluminum foil bags, double-layer PE liners, and export-grade fiber drums, with customizable sizes from 10mg to 25kg.
Q: Do you support OEM or private label services?
A: Yes, we provide OEM/ODM services including custom packaging, labeling, and specification adjustments based on customer requirements.
Q: Can you support regulatory filing (DMF or documentation support)?
A: Yes, regulatory support and technical documentation packages can be provided upon request depending on market requirements.
Q: How do you handle international shipping?
A: We ship globally via air, sea, or express courier, and ensure compliance with international chemical transport regulations.
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